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RESEARCH SERVICES

This is to let you know of the proposal of scientific support that MELISA Institute offers from its new platform on mass spectrometry and proteomics.

MELISA Institute is a private biomedical research center located in Concepción, Chile. It provides a platform that is integrated by a timsTOF Pro mass spectrometer coupled with a nano HPLC (BRUKER Daltonics).

This chromatographic platform allows for the purification of AKTA Avant 25 proteins and a DirectDetect infrared protein quantification system. Furthermore, in the bioinformatics area, we have a high-capacity analysis server and multiple software specialized in protein studies.

This platform is able to massively identify proteins in solution or in gel, through the methods of: Bottom-up proteomics, label free quantification and new sequencing of purified proteins. These provide the ability to increase the spectrum of analysis in the various lines of research.

Until now, research centers requiring these kind of services in Chile had to send their samples to other countries. This involved high transportation costs and the evident risk of loss or degradation.

With this new scientific support offered by MELISA Institute you will be able to avoid these inconveniences and interact in a personalized way with our scientific team. Our headquarters in Concepción significantly reduces shipping costs and the professionalism of our experts guarantees the quality of all proteomic and bioinformatics analysis.

PROTEOMICS PLATFORM

  • timsTOF Pro™ Mas Spectrometry platform (timsTOF Pro™ and nanoHPLC nanoElute™)(Bruker Daltonics™)
  • Preparatory Chromatograpy System ÄKTA Avant 25™ (GE Healthcare Life™)
  • Centrifugal Vacuum Concentrator HyperVAC™ connected to Cold Trap HyperCOOL™
  • DirectDetect™ IR-Spectrometer

List of services: Proteomics Area

  • Extraction and purification of proteins from ultra-complex samples
  • Total proteins identification by Bottom-up proteomics
  • Peptidomics
  • Targeted Proteomics (Selected Reaction Monitoring (SRM))
  • Protein Fractionation

 

Download Proteomic Services

 

GENOMICS PLATFORM

  • NextSeq500™ Sequencer (Illumina™)
  • Automated DNA/RNA Extractor QIAsymphony™ (Qiagen GmbH™)
  • Real-time PCR StepOnePlus™ (Applied Biosystems™)
  • Fragment Analyzer Qsep 100™ (BiOptic Inc.™)

 

BIOINFORMATICS AREA

Bioinformatics or computational biology involves a discipline where the application of computer science and new technologies for the management, simulation, visualization and analysis of large volumes of data of diverse biological nature converge.

Our Bioinformatics platform has a great capacity to analyze data from both the proteomic and genomic areas. Within every working area, MELISA Institute put into practice a workflow where the experimental work converges and a great capacity of data analysis. This flow is made up of processes that manage to combine licensed and freely licensed software in order to obtain reliable results helping us to identify the components of the samples analyzed in the detection stages.

MELISA Institute is capable of providing different types of services in the area of Proteomics, Genomics and Bioinformatics, in order to offer a solution to the development of their research. Our laboratory has the experience and the personnel trained for the analysis of complex samples, both for Proteomics, Genomics and Bioinformatics.

Mass Spectrometry Introduction

Download Proteomic Services

 

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