Proteomics is a rapidly growing field of molecular biology that is concerned with the systematic, high-throughput approach to protein expression analysis of a cell or an organism. Typical results of proteomics studies are inventories of the protein content of differentially expressed proteins across multiple conditions.
The cell responds to internal and external changes by regulating the activity and level of its proteins; therefore changes in the proteome (a collection of all the proteins coded in our genes) provide a snapshot of the cell in action. Proteomics enables the understanding of the structure, function and interactions of the entire protein content in a specific organism.
Proteomics developments have included advances in mass spectrometry (MS) technology, protein fractionation techniques, bioinformatics. Proteomics relies on three basic technological cornerstones that include a method to fractionate complex protein or peptide mixtures, MS to acquire the data necessary to identify individual proteins, and bioinformatics to analyze and assemble the MS data. Most proteomic discoveries and efforts to date have been mainly directed towards the areas of cancer research drug and drug target discovery and biomarker research.
timsTOF Pro™ Mass Spectrometry platform and nanoHPLC nanoElute™ (Bruker Daltonics™)
Preparatory Chromatography System ÄKTA Avant 25™
(GE Healthcare Life™)
DirectDetect™ IR-Spectrometer (Shimadzu™)
Our platform is able to massively identify proteins in solution or in gel, through the methods of Bottom-up proteomics, label-free quantification and new sequencing of purified proteins. These provide the ability to increase the spectrum of analysis in the various lines of research.
Until now, research centers requiring these kinds of services in Chile had to send their samples to other countries. This involved high transportation costs and the evident risk of loss or degradation.
With this new scientific support offered by MELISA Institute, you will be able to avoid these inconveniences and interact in a personalized way with our scientific team. Our headquarters in the Concepción Province significantly reduces shipping costs and the professionalism of our experts guarantees the quality of all proteomics and bioinformatics analysis.
Protein identification service in gel and solution
Protein quantification service (LFQ, TMT, SWATH)
Protein post-translational modification service
Selected Reaction Monitoring
De novo Antibody Sequencing
Cell Surface Proteomics