PUBLICATIONS

Impact of emerging virus pandemics on cause-specific maternal mortality time series: a population-based natural experiment using national statistics, Argentina 1980-2017

THE LANCET, REGIONAL HEALTH, AMERICAS - IMPACT OF EMERGING VIRUS PANDEMICS ON CAUSE-SPECIFIC MATERNAL MORTALITY TIME SERIES: A POPULATION-BASED NATURAL EXPERIMENT USING NATIONAL VITAL STATISTICS, ARGENTINA 1980-2017

"Mortality data on a global scale reflect important advances in the health and life expectancy of the population during the last 50 years. Nonetheless..."

How to reduce maternal mortality in Mexico?

BOOKLET HOW TO REDUCE MATERNAL MORTALITY IN MEXICO

Spanish PDF
English PDF


MELISA Institute is pleased to share with you the results of a natural experiment that includes the description of determining factors to reduce maternal...

Abortion legislation, maternal healthcare, fertility, female literacy, sanitation, violence against women and maternal deaths: a natural experiment in 32 Mexican states

BMJ OPEN – ABORTION LEGISLATION, MATERNAL HEALTHCARE, FERTILITY, FEMALE LITERACY, SANITATION, VIOLENCE AGAINST WOMEN AND MATERNAL DEATHS: A NATURAL EXPERIMENT IN 32 MEXICAN STATES

"Although less permissive states exhibited consistently lower maternal mortality rates, this finding was not explained by abortion legislation itself. Rather,...

Fundamental discrepancies in abortion estimates and abortion-related mortality: A reevaluation of recent studies in Mexico with special reference to the International Classification of Diseases
Women's Education Level, Maternal Health Facilities, Abortion Legislation and Maternal Deaths: A Natural Experiment in Chile from 1957 to 2007

PLOS ONE - WOMEN’S EDUCATION LEVEL, MATERNAL HEALTH FACILITIES, ABORTION LEGISLATION AND MATERNAL DEATHS: A NATURAL EXPERIMENT IN CHILE FROM 1957 TO 2007

“Increasing education level appears to favorably impact the downward trend in the MMR, modulating other key factors such as access...

Consenso salud materna para Chile en el nuevo milenio

CHILEAN JOURNAL OF OBSTETRICS AND GYNECOLOGY - MATERNAL HEALTH CONSENSUS FOR CHILE IN THE NEW MILLENNIUM

“Chile represents a positive evolution in terms of maternal and infant health in last fifty years. This trend in the...

Women's education level, contraceptive use and maternal mortality estimates

PUBLIC HEALTH - WOMEN’S EDUCATION LEVEL, CONTRACEPTIVE USE AND MATERNAL MORTALITY ESTIMATES.

“Finally, it is important to remark that when official records of maternal deaths and live births are reliable and readily...

Popperian epidemiology and the logic of bi-conditional modus tollens arguments for refutational analysis of randomised controlled trials

MEDICAL HYPOTHESES – POPPERIAN EPIDEMIOLOGY AND THE LOGIC OF BI-CONDITIONAL MODUS TOLLENS ARGUMENTS FOR REFUTATIONAL ANALYSIS OF RANDOMISED CONTROLLED TRIALS

“According to this popperian model, the applicability of the randomized controlled trial (RCT) results in clinical practice implies transferring of all...

Impact of education, Income and chronic disease risk factors on mortality of adults: does 'a pauper-rich paradox' exist in Latin American societies?

PUBLIC HEALTH – IMPACT OF EDUCATION, INCOME AND CHRONIC DISEASE RISK FACTORS ON MORTALITY OF ADULTS: DOES ‘A PAUPER-RICH PARADOX’ EXIST IN LATIN AMERICAN SOCIETIES?

 “In this prospective cohort study conducted in a  middle-income  Latin  American country, the protective effect of education was not  ...

Desigualdad educacional y socioeconómica como determinante de mortalidad en Chile: análisis de sobrevida en la cohorte del proyecto de San Francisco

REVISTA MÉDICA DE CHILE – SOCIOECONOMIC AND EDUCATIONAL INEQUITIES AS INDEPENDENT PREDICTORS FOR MORTALITY IN A DEVELOPING COUNTRY. A COHORT STUDY IN SAN FRANCISCO, CHILE

 

Socioeconomic and educational inequities as independent predictors for mortality in a developing country. A cohort study in San Francisco, Chile...

Impact of parity on anthropometric measures of obesity controlling by multiple confounders: a cross-sectional study in chilean women

JOURNAL OF EPIDEMIOLOGY & COMMUNITY HEALTH – IMPACT OF PARITY ON ANTHROPOMETRIC MEASURES OF OBESITY CONTROLLING BY MULTIPLE CONFOUNDERS: A CROSS-SECTIONAL STUDY IN CHILEAN WOMEN

“Parity modestly influences BMI, but does not seem to be related to WC, WHR and WHtR after controlling by confounders....

Early Life and Adult Socioeconomic Influences  on Mortality Risk: Preliminary Report of a 'Pauper Rich' Paradox in a Chilean Adult Cohort

ANNALS OF EPIDEMIOLOGY – EARLY LIFE AND ADULT SOCIOECONOMIC INFLUENCES ON MORTALITY RISK: PRELIMINARY REPORT OF A ‘PAUPER RICH’ PARADOX IN A CHILEAN ADULT COHORT

“These findings suggest a ‘pauper rich’ paradox in transitioning Latin American economies. Income level does not seem sufficient to improve...

Overcoming Barriers in the Management of Hypertension: The Experience of the Cardiovascular Health Program in Chilean Primary Health Care Centers

INTERNATIONAL JOURNAL OF HYPERTENSION – OVERCOMING BARRIERS IN THE MANAGEMENT OF HYPERTENSION: THE EXPERIENCE OF THE CARDIOVASCULAR HEALTH PROGRAM IN CHILEAN PRIMARY HEALTH CARE CENTERS

“The success in improving the BP control to values <140/90 mmHg from 45.3% to 59.7% underscores the contribution of this program...

A landmark for popperian epidemiology: refutation of the randomised Aldactone evaluation study

JOURNAL OF EPIDEMIOLOGY & COMMUNITY HEALTH – A LANDMARK FOR POPPERIAN EPIDEMIOLOGY: REFUTATION OF THE RANDOMISED ALDACTONE EVALUATION STUDY

“This paper presents two studies with contradictory results that are in a synchronic relation, forming a complete logical analysis unit:...

Immunomodulation of T Helper Cells by Tumor Microenvironment in Oral Cancer is Associated With CCR8 Expression and Rapid Membrane Vitamin D Signalin Pathway

FRONTIERS - IMMUNOMODULATION OF T HELPER CELLS BY TUMOR MICROENVIRONMENT IN ORAL CANCER IS ASSOCIATED WITH CCR8 EXPRESSIONS AND RAPID MEMBRANE VITAMIN D SIGNALING PATHWAY

"The immune system plays a key role in the protective response against oral cancer; however, the tumor microenvironment (TME) impairs this anti-cancer response by...

Proteogenomic Analysis in an early onset.jpg

PROTEOGENOMIC ANALYSIS IN AN EARLY ONSET DIFFUSE GASTRIC CANCER PATIENT REVEALED ALTERATIONS IN PIK3R1, TP53, SMAD4 AND A POTENTIAL ROLE OF THE PI3K-AKT AND EGFR PATHWAYS: A CASE REPORT

"Typically, early-onset gastric cancers (EOGC) present at the age of 45 years old or younger. Although its prevalence ranges from 2.7% to 15% depending on the..." 

Analysis of Tumor-Infiltrating T-Cell.jpg

ANALYSIS OF TUMOR-INFILTRATING T-CELL TRANSCRIPTOMES REVEAL A UNIQUE GENETIC SIGNATURE ACROSS DIFFERENT TYPES OF CANCER

"The main role of the immune system is to protect the body against infections and abnormal cell growth and one of the main players in the recognition of pathogenic..."

PROTEOMIC ANALYSIS REVEALS RENIBACTERIUM SALMONINARUM

JOURNAL OF FISH DISEASES - PROTEOMIC ANALYSIS REVEALS RENIBACTERIUM SALMONINARUM GROWN UNDER IRON-LIMITED CONDITIONS INDUCES IRON UPTAKE MECHANISMS AND OVERPRODUCTION OF THE 57-KDA PROTEIN

"Renibacterium salmoninarum, a slow-growing facultative intracellular pathogen, is the causative agent of bacterial kidney disease, a chronic, progressive and..."

PGOD.jpg

PATAGONIAN SHEEPDOG: GENOMIC ANALYSES TRACE THE FOOTPRINTS OF EXTINCT UK HERDING DOGS TO SOUTH AMERICA

"Most modern dog breeds were developed within the last two hundred years, following strong and recent human selection based predominantly on a ..."

TLRHA - CC-LAC.jpg

The Cohorts Consortium of Latin America

and the Caribbean (CC-LAC)

Group of more than 70 professionals and researchers in Latin America and the Caribbean who have carried out cohort studies focused on non-communicable diseases (for example, diabetes or hypertension) and cardiovascular diseases (for example, ischemic heart disease).